Dr. Christian
R. A. Regenbrecht
MOLECULAR BIOLOGIST · TRANSLATIONAL ONCOLOGY
Science. Truth. Responsibility.
Scientist, entrepreneur and executive working at the intersection of translational oncology, functional precision medicine and drug development.
SCIENCE & TRANSLATION
From patient-derived models to functional precision medicine.
01
Patient-derived Models
Patient-derived organoid and ex vivo models that preserve clinically relevant tumour biology.
02
Functional Precision Medicine
Functional testing of individual patient tumours to identify therapeutically actionable vulnerabilities.
03
Translational Oncology
Bridging experimental cancer biology and clinical decision-making through patient-relevant model systems.
04
Drug Development
Translational strategies for evaluating therapeutic response and accelerating evidence-driven drug development.
SELECTED PUBLICATIONS
Selected Publications
2024
Functional Precision Medicine Successfully Guides Therapeutic Regimen of ‘Cancer of Unknown Primary’ Later Classified as Triple-Negative Breast Cancer: A Case Report
Case Reports in Oncology · 17(1), 490–496
2019
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
PLOS Genetics · 15(3), e1008076
2016
Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures
SLAS Discovery · 21(9), 931–941
2021
Context Matters—Why We Need to Change From a One Size Fits All Approach to Made-to-Measure Therapies for Individual Patients With Pancreatic Cancer
Frontiers in Cell and Developmental Biology · 9, 760705
PERSPECTIVE
Science is more than the generation of knowledge.
TRUTH · RESPONSIBILITY · TRANSLATION
Truth is our purpose. Responsibility is what gives science meaning.
I believe that science carries a responsibility beyond discovery. Translational research should connect biological understanding with decisions that matter for patients — rigorously, transparently and with an awareness of the limits of our knowledge.
My work has therefore remained at the intersection of experimental biology, patient-derived models, functional precision medicine and drug development. The common question is simple: how can evidence become meaningful action?
CONTACT
Let’s start a conversation.
For scientific exchange, collaboration and professional enquiries, please feel free to get in touch.
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